Hans Van Der Plyum's side completed back-to-back wins over Liberia's LISCR on Sunday to qualify.
The Ghanaian champions won 3-0 on Sunday at the Newly renovated Berekum Golden City Park to reach the next stage of the competition on their debut.
Goals from Jordan Opoku before the break and a second half double from striker Emmanuel Clottey sealed a comfortable home win for Chelsea.
Chelsea won 2-0 in the first leg in Monrovia and thus finish 5-0 winners on aggregate in the preliminary round qualifier.
